The answer to the question of the kind of column you would like can only be addressed comprehensively. The short answer though includes over the top grade, uniform, high density, low metal porous silica with a developed end capping for the finishing touch. What follows next is a column that can stand extreme conditions while maintaining its functionality in excess of what is expected.
Developments that make it possible to navigate a variety of practical groups and particle sizes allowing for scalability and transferability allows to penetrate all areas of operations between R&D to QC. Particle sizes ranging from 1.6, 2.6 and 5um can do well to provide the necessary support to HPLC and UHPLC analytical systems. The fact that there is variety allows for them to be integrated in different departments in both R&D and QC. What cutting edge columns do is make sure that time to tweak from one particle size to the next is reduced and the conditions are optimal. This can be attributed to the homogeneity of the silica gel, excellent perfomance, end capping and bonding of functional groups that keep the predictable consistency where columns are concerned.
With the aid of suitable column sizes , standard resolution can be made constant as shifts are made among particle sizes. This property seeks to facilitate the movement of methods among different sizes of the particles. In bid to make accurate calculations of the flow and gradient , chromatography software is used to give a determination. As one is using UPHLC during R&D and HPLC during quality control , the time used up to re-align analytical conditions in conjunction with optimal resolution is recovered.
The company you purchase from when you make the decision to do so matters. Experienced industry players are the best companies to work with when seeking to buy these columns. Those that are known to make columns from basic silica gel. Companies that offer the right customer support are definitely keepers. Next level companies will not just stop at the questions but will want to know how their product fared and what you as a customer truly appreciate in their products and services. The hierarchy now goes to the next level with these players using the information they have harnesses to develop products that take your experience with them to the next level in terms of taste and preference . These may just be the gamechangers of the industry. In all of that your take away would be to go for a company that serves your interest both money wise and of course product wise.